Which of the following statement is/are correct regarding Gray Babies syndrome?
I- Occurs in premature and new born infants when choramphenicol is administrated during the first few days of life
II- Due to inability of the infant to metabolize the drug because of glucoronyl transferase deficiency
III- Glucoronyl transferase is required to detoxify cloramphenicol
Drugs shown to be effective in the prevention of Travellers'
Diarrhea, which might have been prescribed for SM include:
I doxycycline
II cotrimoxazole
III amoxicillin
Correct administration of Penicillamine in the treatment of rheumatois arthritis include:
The fraction of bound receptors in a well-defined drug-receptor binding system is determined by:
I the equilibrium drug-receptor dissociation constant
II the free drug concentration
III the total receptor concentration
Which of the following vitamin has its chemical structure related to PABA?
Biological catalysts responsible for supporting almost all of the chemical reactions that maintain human life process:
Catabolism of carbohydrates is a process characterized by:
I- Consume of energy
II- Release stored energy from carbohydrates
III-Glycogenolysis is an example of carbohydrates catabolism reaction
Which of the following amino acid is an important precursor of hemoglobin?
Vitamin that requires an intrinsic factor to be carried out to ileum in order to suffer absorption from the small intestine:
Which of the following is an antiviral drug used in the treatment of AIDS-HIV?
I- Acyclovir
II- Zidovudine
III- Stavudine
In which of the following organs or tissues is the action of acetylcholine NOT described as "nicotinic"?
I Motor endplates of skeletal muscle
II Celiac ganglia
III Circular muscles of the iris
The pharmacist fills a prescription for sumatriptan 100 mg tablets for a migraine patient. Appropriate information to provide to the patient includes which of the following?
Otitis media is an ear infection normally caused by S. pneumoniae and may be best treated by:
Potassium-sparing diuretics:
I exert their effect in the proximal tubule.
II may cause intracellular alkalosis.
III include the aldosterone antagonists.
Diseases which are viral infections include:
I poliomyelitis
II rabies
III Legionnaires' disease
Viral encephalitis, a CNS infection, may be best be treated by which of the following agents?
Which of the following is considered the FIRST precursor of vitamin A formation?
Resistance is the major problem with penicillins due to ability of bacteria to breakdown the lactam ring of penicillin and inactivates the drug. To overcome these problem penicillins can be administrated together with β-lactamase inhibitors.
Examples of β-lactamase inhibitors is/are:
I- Clavulanic acid
II- Sulbactam
III- Tazobactam
Which of the following is not directly related to a drug toxicity of Nitroglycerin?
Given F = .24, what is the overall hepatic clearance of morphine if the above patient has portal hypertension such that their hepatic blood flow is reduced by ½? Assume the clearance value given in the previous question is entirely hepatic clearance.
Which Cytochrome P450 isozyme does not participate appreciably in drug metabolism?
Drug considered as the drug of choice in a specific asthma emergency treatment include:
Condition characterized by a reversible form of airflow obstruction is known as:
The style of management in which the owner of a pharmacy emphasizes the development of detailed policies and written procedures for employees to observe at all times is referred to as:
Goals of gout treatment may include:
I- Reduce inflammation during acute attacks
II- Accelerate renal excretion of uric acid
III- Reduce the conversion of purine to uric acid
Autoimmune disorders include which of the following?
I Graves' disease
II Systemic Lupus Erythematosus
III Osteoarthritis